By R T Blickenstaff

Antitumor Steroids examines using steroids, in addition to nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the remedy of melanoma. It explains the mechanism wherein steroids and their receptors interact to impact their physiological capabilities typically and their antitumor job specifically. It additionally describes the systematic screening of antitumor compounds remoted from normal resources.
Organized into 9 chapters, this publication starts off with an summary of the position of steroids in melanoma remedy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the following chapters reflect on androgens, a few antiandrogens, derivatives in accordance with C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl staff. The publication explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor houses of certainly happening corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The ebook concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This booklet is a useful source for natural and medicinal chemists biochemists, and pharmacologists attracted to using steroids in treating cancer.

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Antitumor Steroids by R T Blickenstaff


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