
By Kimberley Jade Powell
This thesis addresses primary medical questions such as:
How are complicated ordinary items synthesized in vivo?
Can we mirror those stipulations in a laboratory environment?
What is the organic functionality of such secondary metabolites?
What are the organic origins of chirality?
These concerns are explored in an obtainable demeanour utilizing a multidisciplinary process spanning chemistry, biology and physics to enquire an enticing kinfolk of complicated typical items remoted from marine molluscs – the tridachiahydropyrones.
The paintings has achieved:
Elegant biomimetic syntheses of the various tridachiahydropyrone compounds in vitro utilizing natural synthesis techniques
The characterization of the interactions among those compounds and various version membrane structures utilizing a chain of fluorescence spectroscopic studies
The research of the antioxidant and photoprotective homes of the compounds through biophysical assay techniques
The synthesis of tridachiahydropyrone using the version membrane platforms as biomimetic response media.